GloFish do well in a diverse amount of aquarium environments ranging from simple desktop aquariums of a couple of gallons, all the way to large planted tropical aquariums. The natural habitat of Glofish varies depending on seasonal rains as they spend the dry season in larger streams and tributaries, while venturing out into floodplains and smaller water ways during the wet season. They do not have specific aquarium decor requirements, but will appreciate the presence of plants, driftwood, rocks and other similar decor in order to give them someplace to retreat when threatened.
GloFish have only basic needs when it comes to filtration and water movement, with any aquarium designed to house tropical community fish being suitable. Tank mates should include other peaceful to semi-aggressive fish species that are not large enough to consider the them as food. Glofish school in nature, thus they prefer to be kept in groups of 8 or more individuals.
They will typically live longer if kept in groups or small schools and are generally considered more interesting to watch while swimming in tight groups. While GloFish are genetically modified for appearance and selectively bred to enhance that appearance, they are just like Zebra Danio in terms of aquarium care, tank mates and feeding.